Side effects in adults may include fluid retention, joint pain and nerve compression symptoms. There is theory that HGH treatment may increase the risks of diabetes or cancer, especially in those with other predispositions treated with higher doses. It is pointed out, moreover that diabetes is a disease that develops over perhaps 30 or 40 years of poor eating habits, and the most likely cause of diabetes is the poor nutrition which the patient had prior to the use of growth hormone. One survey of adults who had been treated with replacement cadaver GH (which has not been used anywhere in the world, since in the early 80's) during childhood showed a mildly increased incidence of colon cancer, but linkage with the HGH treatment was not established